ICSI – Intracytoplasmic Sperm Injection (ICSI) involves the direct injection of a single sperm into each egg under direct microscopic vision. ICSI makes it possible to fertilize eggs with sperm derived from men with the severest degrees of male infertility.
In cases of absent Vas deferens (sperm collecting ducts), obstructed Vasa deferentia (ducts carrying sperm from testicles to the urethra for ejaculation), or impotency, ICSI can be performed with sperm obtained through Testicular Sperm Extraction (TESE) or Testicular Sperm Aspiration (TESA). In such cases, the birth rate is usually no different than when IVF is performed for indications other than male infertility. The successful performance of ICSI requires a high level of technical expertise by those in the embryology lab.
The success rate varies depending on the cause and ranges between 35-50% per cycle. No major differences in birth, behavior problems, or parental stress were found between the children conceived with infertility treatments and those conceived naturally.